Latest News

Welcome on Board Philippe !

We are pleased to announce that Philippe Pierrillas is now a member of the Calvagone Team. Philippe received his PhD training from the University of Lyon and is joining us upon completion of a postdoctoral research period at the Pharmacometrics Research Group in Uppsala, Sweden, where he worked closely with Professors Mats Karlsson, Lena Friberg and Andy Hooker. We are very happy to have him in our team of consultants.

October 24, 2017

Meet us at PAGE 2017 in Budapest!

Erno and Christian will be at PAGE in Budapest from June 6 to 9. You can meet them at the venue, during poster sessions on Wednesday afternoon (II-44) and Thursday morning (III-62) or contact us directly to schedule a meeting.

May 24, 2017

2nd European course on Pharmacokinetics and Pharmacodynamics of Protein Therapeutics. Principle and Pharmacometric Approaches. August 29-31, 2017, Darmstadt, Germany.


This second 3-day course will introduce participants to basic principles in the pharmacokinetics and pharmacodynamics of novel therapeutic proteins and provide opportunities for basic hands-on exercises in the PK/PD evaluation of these compounds. Topics include target-mediated drug disposition, tissue and tumor penetration, first-in-human dose selection, immunogenicity, clinical pharmacology challenges, biosimilars, and drug-drug interactions. Hands-on exercises and simulations will be performed individually and in small groups using simple software tools (no prior experience required).

The course is a shortened version of the week-long course on ‘Pharmacokinetics and Pharmacodynamics of Protein Therapeutics - Concepts and Hands-On Modeling and Simulation’ that Drs. Meibohm and Gabrielsson have offered for the last seven years in the United States. Christian will co-host this course together with Pascal Girard and Maike Puetter from Merck.

May 11, 2017

We obtained Crédit Impôt Recherche (CIR) accreditation

On April 3 2017, we received Crédit Impôt Recherche (CIR) accreditation from the French Ministère de la Recherche for the period 2017 up to 2019. CIR is a French governmental initiative to promote partnership between companies on Research and Development oriented projects. If you want to read more, please visit:

April 11, 2017

Kick-Off Meeting for DDMoRe Foundation on 17th of January 16:30 (CET)

The DDMoRe Foundation will initiate 3 Community groups to facilitate community initiatives to support developement of:

- Languages: progress the standards (MDL, PharmML, SO and Prov-O)

- Model Repository: enhance the repository content and improve the suer experience

- Thoughtflow: take the proof of concept ot the next level

You are very welcome to participate to this Kick-Off Meeting !

January 11, 2017

Welcome on Board Erno !

We are very pleased to announce that Erno van Schaick is now a member of the Calvagone Team.

December 5, 2016

Clinical Trial Simulation Training at Lyon University

In collaboration with Exprimo (Ruben Faelens), a 2-hour session in Clinical Trial Simulation was organized at Lyon University as part of the Master's program curated by Emilie.

The 10 students managed to explore the PK model for Sunitinib. Four students struck gold at the end, managing to create an efficient design that proved biosimilarity.

November 24, 2016

Poster presentation of nlmixr R package at WCoP 2016

nlmxr is an open-source R package for population PK/PD modelling developped by Wenping Wang and Yuan Xiong, in collaboration with Occams (Rik Schoemaker and Justin Wilkins).

Christian, at that time as an Exprimo member, has built a bunch of simulated datasets from a large panel of PK and PK/PD models and some of them were used to challenge nlmxr.

October 20, 2016